DNA leaks before capsids pop: AAV thermal stability on Uncle

APPLICATION NOTE Explore AAV buffers and stability with Big Tuna and Uncle Introduction A Adeno-associated virus (AAV) vectors endure a lot of stress when exploring the unknowns of a purification process: buffer salts, pH and ionic strength all impact stability…

One-stop stability Cracking stability using a pile of one-trick, sample-hungry tools is a ton of work. Uncle combines 3 different measurement modes — fluorescence, SLS and DLS. So you can crank out all your data in just a few hours,…

Epic Gene Therapy Tools Combine and conquer Stunner is the only system that pulls together UV/Vis concentration, dynamic light scattering (DLS) and static light scattering (SLS) data from the same 2 µL sample. Dig in to your AAV by bringing…

APPLICATION NOTE Meet Aunty – the Queen of protein stability Introduction Aunty is the fastest, highest throughput protein stability platform on the planet (Figure 1). Other stability methods each have their drawbacks: some are slow, others don’t give the full…