Soup-up AAV & LNP sample prep with Big Tuna

Epic Gene Therapy Tools Combine and conquer Stunner is the only system that pulls together UV/Vis concentration, dynamic light scattering (DLS) and static light scattering (SLS) data from the same 2 µL sample. Dig in to your AAV by bringing…

APPLICATION NOTE Explore AAV buffers and stability with Big Tuna and Uncle Introduction A Adeno-associated virus (AAV) vectors endure a lot of stress when exploring the unknowns of a purification process: buffer salts, pH and ionic strength all impact stability…

Cut loose from manual buffer exchange Buffer exchange and sample concentration are the time consuming, hands-on chores you have to deal with before all the things you really want to do. Big Tuna is a fully automated, high-throughput buffer exchange…

Application Note Fast track formulation pH screening with automated buffer exchange on Big Tuna Introduction The critical process of screening formulation buffers to optimize stability is labor intensive and time consuming, which are often limiting factors in biologics development. The…