Aunty protein stability characterization tool

APPLICATION NOTE Meet Aunty – the Queen of protein stability Introduction Aunty is the fastest, highest throughput protein stability platform on the planet (Figure 1). Other stability methods each have their drawbacks: some are slow, others don’t give the full…

One-stop stability Cracking stability using a pile of one-trick, sample-hungry tools is a ton of work. Uncle combines 3 different measurement modes — fluorescence, SLS and DLS. So you can crank out all your data in just a few hours,…

Tech Note Meet Our Uncle: 12 Stability Applications on One Platform Uncle is an all-in-one stability platform that enables twelve different applications with one instrument. Fluorescence, static light scattering (SLS) and dynamic light scattering (DLS) detec­ tion methods are used…

APPLICATION NOTE Conquer ADC stability characterization with Aunty Introduction Conjugating potent cytotoxic payloads to monoclonal antibodies results in powerful anti-cancer therapeutics, but the resulting antibody-drug conjugates (ADCs) have unique stability challenges.1 Attaching a hydrophobic small molecule drug to a hydrophilic…