Study of Protein Conformation with FT-IR

Application Note AN B401 An insight into the (un)stable protein formulation The Fourier-Transform Infrared (FTIR) spectroscopy is a very sensitive method in the field of protein-biochemistry. It allows profound statements about the secondary structure of proteins in aqueous solutions as…

Application Note AN B407 Biomolecules, Cells and Tissue Studied by IR-Spectroscopy For more than 30 years, molecules have been analyzed in the solid, liquid and gaseous state on the basis of their specific vibrations. So, the (FT-) IR spectroscopy has…

Application Note Biopharmaceuticals Aggregation Analysis of Innovator and Biosimilar Therapeutic Proteins Using FTIR Measurement of rituximab aggregation in concentrated samples using the Agilent Cary 630 FTIR spectrometer Authors Aveline Neo and Ravindra Gudihal Agilent Technologies, Inc. Abstract Protein aggregation can…

Compendium BioPharmaceutical approach with spectroscopy Summary Heavily-regulated biopharmaceutical manufacturers are increasing their use of molecular spectroscopy techniques, including both vibrational spectroscopy and UV-Visible spectrophotometry. These analytical methods include the use of mid-infrared (MIR), near infrared (NIR), Fourier transform infrared (FTIR),…