Simultaneous Determination of Five Genotoxic Aryl Sulfonate Impurities in Pharmaceuticals by LCMS-2050

Coupling Mass Detection with UV to Improve Method Sensitivity for Esters of Benzenesulfonic Acid in Analysis of Genotoxic Impurities Margaret Maziarz and Mark Wrona Waters Corporation, Milford, MA, USA A P P L I C AT I O N B…

LAAN-J-MS-E018B GCMS Gas Chromatograph Mass Spectrometer Analysis of Potential Genotoxic Impurities in Active Pharmaceutical Ingredients 18B Chemicals such as methanesulfonic acid (mesylate), benzenesulfonic acid (besilate), and p-toluenesulfonic acid (tosylate) are used in the process of synthesizing active pharmaceutical ingredients. These…

PO-CON1791E Analysis of Genotoxic Impurities like Ethane Sulfonic acid esters in pharmaceutical substance by GC-MS/MS ASMS 2017 TP 170 Prashant Hase, Ankush Bhone, Durvesh Sawant, Dheeraj Handique, Sanket Chiplunkar, Nitish Suryawanshi, Ajit Datar, Jitendra Kelkar and Pratap Rasam Shimadzu Analytical…

[ TECHNOLOGY BRIEF ] Analysis of Genotoxic Impurities by an ACQUITY QDa Mass Detector with Integrated ACQUITY Diverter Valve Margaret Maziarz and Mark Wrona Waters Corporation, Milford, MA, USA Minimize potential sources of contamination and mitigate chances of ion suppression…