Measurement of Oligonucleotide Impurities Using Shimadzu Nexera XS Inert Coupled To LCMS-9030 QTOF

High Performance Liquid Chromatograph Mass Spectrometer Application News Analysis of Oligonucleotides Using a Single Quadrupole Mass Spectrometer with Hydrophilic Interaction Chromatography (HILIC) Mizuki Hayakawa, Noriko Kato, Kosuke Uchiyama User Benefits  Synthetic oligonucleotides and impurities can be analyzed using HILIC.…

Liquid Chromatograph Mass Spectrometer LCMS-9050 Application News Analysis of mRNA 5’ Cap Structure Using a Quadrupole Time-of-Flight Mass Spectrometer Junna Nakazono User Benefits  The LCMS-9050 quadrupole time-of-flight mass spectrometer and the LabSolutions Insight™ Biologics analysis software enable characterization of…

High Performance Liquid Chromatograph Mass Spectrometer Application News Analysis of Oligonucleotide Impurities Using Single Quadrupole Mass Spectrometer Mizuki Hayakawa, Hiroyuki Niwa User Benefits  Combination use of LCMS-2050 single quadrupole mass spectrometer and LabSolutions Insight Biologics provides comprehensive characterization of…

Impurity Profiling and Characterization of Therapeutic Oligonucleotides using Nominal Mass Spectrometry on a Single Quadrupole LC-UV-MS system Risa Suzuki1, 3, Kosuke Uchiyama1, Noriko Kato1, Simon Ashton2, Neil Loftus2, Yuka Fujito1 1Shimadzu Corporation, Kyoto, Japan; 2Shimadzu Corporation, Manchester, United Kingdom; 3Shimadzu…