Rapid LC-MS Analysis of Glycoproteins With a 20 mm Wide Pore HILIC Column

Developing High Resolution HILIC Separations of Intact Glycosylated Proteins Using a Wide-Pore Amide-Bonded Stationary Phase Matthew A. Lauber, Scott A. McCall, Bonnie A. Alden, Pamela C. Iraneta, and Stephan M. Koza Waters Corporation, Milford, MA, USA A P P L…

Biomolecule Purification, Characterization, and Analysis Innovative Technologies from the Leader in Separation Science and Analytical Biochemistry Advances in the areas of genomics, proteomics, metabolomics, and molecular and system biology continue to revolutionize the diagnosis and treatment of diseases and increase…

Waters Application Notes Glycans There are a variety of complementary techniques practiced to get the complete story about a glycoprotein. Each technique varies in complexity and provides a different layer of information. Method complexity This application notebook highlights a body…

MAIN MENU TABLE OF CONTENTS [ APPLICATIONS NOTEBOOK ] BIOSEPARATIONS Tools, Techniques, and Insights into Biopharmaceutical Analysis INT RODUCTION Biopharmaceuticals have emerged as a dominant class due to their specificity and efficacy. T he production of biopharmaceuticals, however, is distinctly…