Column Selection for RPLC-UV Impurity Analysis of Fatty Acid Modified GLP-1 Receptor Agonists

Application Note Temperature Dependence on ReversedPhase Separations of Fatty Acid Modified GLP-1 Receptor Agonists and Their Impurities Caitlin M. Hanna, Stephan M. Koza, Steve Shiner Waters Corporation Abstract Here, we show that the reversed-phase separation of fatty acid modified GLP-1…

Application Note Reversed-Phase LC-MS Analysis of LowAbundance Impurities in a GLP-1a Therapeutic Using a Charged Surface 230Å Superficially Porous Phenyl-Hexyl Column Stephan M. Koza, Stephen J. Shiner, Matthew A. Lauber Waters Corporation, United States Published on July 15, 2026 Abstract…

Agilent biopharma solutions Complete Analytical Workflows for GLP-1 Receptor Agonists Applications for peptide characterization, purification, and bioanalysis Contents Introduction 03 1 Identity, Purity, and Impurity Assessment 06 1.1 1.2 Introduction  Molecular Weight Confirmation of a Peptide Using MS Spectral…

Poster Reprint ASMS 2026 ThP 213 Effect of column chemistry, temperature, inert flow path, and mobile phase on the separation of GLP-1 peptides and their impurities Ace G. GalermoI; Oscar PotterI; Charu KumarI; Randall RobinsonII; Mohammad-Aref KhalilyIII; Shawn EhlersCheangI; Chenchen…