LC-MS Analytics in Bioprocessing: Automation-Driven Analysis of Product Quality Attributes and Nutrient Monitoring

AUTOMATING SAMPLE PREP AND DEMYSTIFYING LC-MS ASSAYS FOR FASTER DATA ANALYTICS IN BIOPRODUCTION Elizabeth Embrey, Yun A Alelyunas, Jurgen Sanes, Caitlyn Da Costa, Guillaume Mignard, Andrea Nardinocchi, Adrien Pegaz-Blanc, Giorgio Horak, Patrick Boyce, Mark D. Wrona INTRODUCTION Automation is highly…

ENHANCING BIOPROCESS DEVELOPMENT THROUGH AUTOMATED SPENT MEDIA AND TITER ANALYSIS BY LC-MS WITH DATA CONNECTIVITY VIA STATISTICAL SOFTWARE Authors: Guillaume Bechade1, Elizabeth Embrey1, Yun A Alelyunas2, Jurgen Sanes4, Caitlyn Da Costa1, Guillaume Mignard3, Andrea Nardinocchi3, Adrien Pegaz-Blanc3, Giorgio Horak3, Patrick…

[APPLICATION NOTEBOOK] At-line Solutions for Upstream Bioprocessing Application Notes [APPLICATION NOTEBOOK] Introduction Bioprocessing harnesses the power of living cells to manufacture valuable products such as biological drugs for clinical use. The introduction and use of biologics has revolutionized biotherapeutics to…

Application Note Analytical LC-MS Platform Methodologies to Support Upstream Bioprocess Optimization Yun Alelyunas, Julie Wushensky, Jurgen Sanes, Mark Wrona, Rui Chen Waters Corporation, United States Published on August 18, 2025 Introduction Effective process monitoring and product critical quality attribute analysis…