Determination of mRNA Encapsulation Efficiency with the Agilent 1290 Infinity II Bio LC System

Application Note Biopharmaceuticals LC/MS Analysis of Lipid Composition in an mRNA LNP Formulation: A Stability Study Authors Li Zhang and Yi Yan Yang Bioprocessing Technology Institute Suresh Babu C.V. and Ravindra Gudhial Agilent Technologies, Inc. Abstract Lipid-based nanocarriers, known as…

Application Note Biopharma Analysis of Lipid Nanoparticle Composition Author Sonja Schneider Agilent Technologies, Inc. 0 DLin-MC3-DMA DMG-PEG 2000 DSPC ×102 4.75 4.50 4.25 4.00 3.75 3.50 3.25 3.00 2.75 2.50 2.25 2.00 1.75 1.50 1.25 1.00 0.75 0.50 Cholesterol Response…

Application Note Biopharmaceuticals Analysis of Lipid Nanoparticle Components Using an Agilent 6545XT AdvanceBio LC/Q-TOF Authors Li Zhang and Yi Yan Yang Bioprocessing Technology Institute, Agency for Science, Technology, and Research (A*STAR) Republic of Singapore Suresh Babu C.V. and Ravindra Gudhial…

APPLICATION NOTE Flexible nanoparticle development: process optimization & scale-up of a wide range of synthetic nanomedicines with Sunshine Introduction In contrast, by using microfluidic technology to combine reactants in a precise mixing geometry using stable, highly controlled, laminar flows, the…