Efficient Use of pH Gradients in the Ion Exchange Analysis of Proteins

[ APPLICATION NOTE ] Development of Monoclonal Antibody Charge Variant Analysis Methods Using a BioResolve SCX mAb Column Hua Yang, Bill Warren, and Stephan Koza Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION Method development parameters for cation Charge heterogeneity…

ACQUITY UPLC H-Class Bio System Built for your biomolecular characterization t he BIocoM PAt IBle u P lc P lAt FoRM The ACQUITY UPLC® H-Class Bio System – the latest extension to the family of ACQUITY UPLC Systems, brings the…

[ APPLICATION NOTE ] Auto•Blend Plus Technology for Ion-Exchange Chromatography Method Development and Robustness Testing Hua Yang, Bill Warren, and Stephan Koza Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ INTRODUCTION Auto•Blend™ Plus Technology Ion-exchange chromatography (IEX) is widely used…

Biomolecule Purification, Characterization, and Analysis Innovative Technologies from the Leader in Separation Science and Analytical Biochemistry Advances in the areas of genomics, proteomics, metabolomics, and molecular and system biology continue to revolutionize the diagnosis and treatment of diseases and increase…