Genotoxic impurity analysis

APPLICATION NOTE 73991 LC-MS/MS method for the quantification of 10 nitrosamine impurities in metformin Authors: Varun Khali, Manoj Kushwaha, Dr. Sachin Pandey, Sunil Kumar, Dr. Biswajayee Patra Thermo Fisher Scientific India Private Limited, Mumbai, India Keywords: Nitrosamine, metformin, nitrosamine impurity,…

APPLICATION NOTE 74059 Highly sensitive and robust LC-MS/MS solution for quantitation of nitrosamine impurities in metformin drug products Authors: Hao Yang1, Edmund Moy1, Michael Volny1, Claudia Martins1, Min Du2, Wael Elmasri3, Tanya Tadey4 Thermo Fisher Scientific, San Jose, CA; Thermo…

Application note | 003215 Pharma Highly sensitive method for the determination of 12 nitrosamine impurities in multiple ARBs, the class of sartan drug formulations Application benefits Authors Varun Khali , Manoj Kushwaha , Dr. Sachin 1 1 • Single method…

Smart note | 002512 Pharma Analysis of genotoxic impurities in pharmaceuticals Accurate, reliable, and confident quantification with high-resolution mass spectrometry Genotoxic impurities—nitrosamines, azido, and nitroso drug substance related impurities: analytical challenges and an accurate and reliable solution to analyze them…