Ion chromatography determination of nitrate and nitrite in metformin API and tablets

White paper | 000025 Ion chromatography determination of nitrate and nitrite in ranitidine drug substance and drug products Authors: Dr. Chetan Chavan, Dr. Chanakya Thaker, and Mr. Chetan Chaudhari; Thermo Fisher Scientific, Powai Mumbai, India Keywords: Dionex ICS-6000, n-nitrosamine, NDMA,…

APPLICATION NOTE 73987 Determination of nitrite in pharmaceuticals Authors: Jingli Hu and Jeffrey Rohrer Thermo Fisher Scientific, Sunnyvale, CA, USA Keywords: Dionex ICS 6000 HPIC system, Dionex IonPac AS19-4µm column, losartan, metformin, ranitidine, diphenhydramine, ADRS 600 suppressor, ion chromatography, n-nitrosamine,…

Application note | 004315 Ion chromatography Determination of nitrite and nitrate from lactose by ion chromatography using the NGES-A suppressor Authors Introduction Chanakya Thaker and Neil Rumachik Nitrite (NO₂⁻) and nitrate (NO₃⁻) impurities in pharmaceutical excipients are of growing Thermo…

Pharma and biopharma Nitrosamine impurities analysis solutions guide • Find the right analytical solution for each stage of nitrosamine impurity analysis • Confidently detect and quantify genotoxic impurities in active pharmaceutical ingredients and finished drug products Contents Advancing confidence in…