Nano and Microscale Peptide Mapping by LC-UV-Orbitrap-Astral Detection of Monoclonal Antibodies with Fraction Collection for Detailed Analysis

Optimizing plant phosphoproteomic data independent acquisition: micro-pillar array columns and traditional packed bed technology Craig P. Dufresne1, Mohana Talasila3, Brett Larsen2, R. Glen Uhrig3,4 1Thermo Fisher Scientific, West Palm Beach, FL; 2Thermo Fisher Scientific, Mississauga, ON, Canada; 3University of Alberta,…

Improving high-throughput Top-Down proteomics using a modified hybrid quadrupole-ultra-high-field-Orbitrap mass spectrometer Eugen Damoc1, Kyle L. Fort2, Michiel van de Waterbeemd2, Sem Tamara2, Christian Thoeing1, Erik Cousijn1, Tabiwang Arrey1, Alexander Harder1, Albert J. R. Heck2 and Alexander Makarov1 Fisher Scientific (Bremen)…

Middle-down Analysis of Monoclonal Antibody Middle using Nano-flow Liquid Chromatography and a Novel Tribrid Orbitrap Mass Spectrometer Jie Qian,1 Keith A. Waddell, 2 Zhiqi Hao2 1 Thermo Fisher Scientific, Somerset, NJ, 2Thermo Fisher Scientific San Jose, CA Overview Results Purpose:…

Poster Note 64778 Top-down Characterization of Monoclonal Antibody on an Orbitrap Fusion Lumos™ Tribrid Mass Spectrometer Seema Sharma, Stephane Houel, Christopher Mullen, Chad Weisbrod, Romain Huguet, John Syka, Dave Horn, Jonathan Josephs, Jae Schwartz, Vlad Zabrouskov Thermo Fisher Scientific, San…