Measuring the Interaction Between Thrombin-α and an Anti-Thrombin Antibody

Light Scattering for the Masses ® Does Antithrombin III Block the Action of a Monoclonal Anti-Thrombin Antibody? Summary Multi-angle light scattering (MALS) is a powerful tool for quantifying multiple types of protein-protein interactions. In a previous application note, we described…

A P P L I C AT I O N N O T E AN3008: Metacomplex Formation & Binding Affinity of Multivalent Binding Partners Sophia Kenrick, Ph.D. and Dan Some, Ph.D., Wyatt Technology Summary Multivalent binding plays a crucial role…

AN3002: Understanding antibody and viral glycoprotein interactions using CG-MALS Kathryn M. Hastie, Ph.D., and Erica Ollmann Saphire, Ph.D., The Scripps Research Institute Summary Viral glycoproteins are often the only antigen found on the viral surface and, as such, are key…

Light Scattering for the Masses ® Binding Affinity and Stoichiometry of a Multivalent Protein-aptamer Association Summary ecause proteins are often multimeric in their native state, the biomarker targets of many pharmaceuticals present multiple binding sites. In the case of monoclonal…