RT-MALS end-point determination of a polysaccharide depolymerization process

W H I T E PA P E R WP8007: RT-MALS − Real-time product attributes, from lab to plant Dan Some, Ph.D., Waters | Wyatt Technology updated October 2023 Summary Process analytical technologies are a key enabler of QbD and…

RT-MALS: Real-Time Process Analytics and Control for Vaccine Nanoparticles and Macromolecules Daniel Some – Wyatt Technology Corporation [email protected] Conclusions Abstract • RT-MALS provides a continuation to PD and Mfg. of detailed analytical characterization by SEC- or FFF-MALS Analytical techniques combining…

Characterizing Vaccines with the Light Scattering Toolkit Biophysical analysis aids in discovery, development and production 1 Table of Contents Introduction 3 Chapter 1: The light scattering toolkit 5 Multi-angle light scattering: Molar mass, radius and beyond 6 Dynamic Light Scattering:…

A P P L I C AT I O N N O T E AN8006: In-line monitoring of liposome size by RT-MALS In liposome and lipid nanoparticle (LNP) drug-delivery applications, particle size is a critical quality attribute (CQA) that impacts…