DMT-on Purification of Phosphorothioate Oligonucleotide Using SHIMSEN Styra HLB SPE Cartridge

Application Note Biologics and Biosimilars High Resolution Separations of Oligonucleotides using PL-SAX Strong Anion-Exchange HPLC Columns Authors J. Massi and L. Lloyd Agilent Technologies, Inc. Introduction Oligonucleotides are synthesized on solid phase supports using an automated procedure of sequential addition…

Clarity BioSolutions For Synthetic DNA/RNA Advance Your Oligonucleotide Work From Sample Preparation to Analysis and Purification Optimized Oligonucleotide Purification and Analysis Designed to efficiently and effectively purify or characterize synthetic oligonucleotides, the Clarity BioSolutions Sample Preparation and LC portfolio includes…

Agilent AdvanceBio Oligonucleotide Columns and Oligonucleotide Standards IMPROVE RELIABILITY. REDUCE COSTS. INCREASE FLEXIBILITY. AGILENT ADVANCEBIO OLIGONUCLEOTIDE COLUMNS AND OLIGONUCLEOTIDE STANDARDS HIGH-RESOLUTION OLIGONUCLEOTIDE SEPARATIONS WITH LONG COLUMN LIFETIME ON HPLC AND UHPLC SYSTEMS Synthetic oligonucleotides are promising therapeutic agents for the…

[ APPLICATION NOTEBOOK ] APPLICATION SOLUTIONS FOR OLIGONUCLEOTIDES Table of Contents Introduction – UPLC Analysis of Synthetic Oligonucleotides......................................................................................................................... 4 [ HPLC & UPLC Separations ] Real-Time Analysis of RNAi Duplexes ....................................................................................................................................................................... 8 Semi-Preparative Scale Single-Stranded RNA Purification .......................................................................................................................... 11 Oligonucleotide…