TRM - Bi, In, 6Li, Sc, Tb, Y - Aqueous calibration solution ASTASOL® ASTASOL® INT-MIX6

Significance of the topic

A reliable multi-element calibration solution is essential for accurate quantification in atomic spectrometric and electroanalytical methods. Certified reference materials like ASTASOL® INT-MIX6 provide traceability, low uncertainty and standardized performance across laboratories.

Objectives and overview

This identification sheet, compliant with ISO Guide 31, documents the preparation, characterization and intended use of ASTASOL® INT-MIX6, a six-element aqueous calibrator. Key details include batch information, concentration assignments and uncertainty estimates.

Methodology and instrumentation

The solution is prepared gravimetrically from high-purity primary compounds (Bi, In, 6Li, Sc, Tb, Y) in a 5% HNO3 matrix. Traceability is established through comparison with certified reference materials (AN 9008(1N), AN 9026(1N), AN 9030(1N), AN 9052(1N), AN 9058(1N) and AN 9067(1N)), all linked to NIST SRMs.

Instrumentation used

• Atomic Absorption Spectrometry (AAS)
• Atomic Emission Spectrometry (AES)
• Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES)
• Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

Main results and discussion

• Assigned concentration for each element: 100.0 mg/l with an expanded uncertainty of ±0.5 mg/l at 20°C.
• Trace impurities are maintained below 0.2 mg/l to ensure high purity.
• Homogeneity and stability demonstrated over the full shelf life under specified storage conditions.

Benefits and practical applications

• Enables accurate calibration for a wide range of atomic spectrometric and selected electroanalytical techniques.
• Reduces complexity by combining multiple elements into a single standard solution.
• Supports compliance with ISO 9001 and ISO 17034 quality management requirements.

Future trends and opportunities

• Expansion of multi-element panels to address emerging analytes in advanced applications.
• Integration of certified solutions into automated calibration systems for high-throughput labs.
• Development of stability-indicating calibrants for speciation and matrix-specific analyses.

Conclusion

ASTASOL® INT-MIX6 offers a traceable, homogeneous and stable multi-element calibration solution with certified values and low uncertainty. Its compliance with international standards and broad applicability make it a valuable tool for precise analytical measurements.