High-sensitivity low-nano flow LC-MS methods for high-throughput sample-limited proteomics

A high-sensitivity high-throughput LCMS platform for single-cell proteomics and low sample amount analysis Runsheng Zheng1, Christopher Pynn1, Manuel Matzinger2, Karl Mechtler2, Alexander Makarov3, Wim Decrop1, Alec Valenta1, Martin Samonig1 1Thermo Fisher Scientific, Germering, Germany; 2Institute of Molecular Pathology, Vienna, Austria;…

Technical note | TN003329 Mass spectrometry High-resolution DIA proteomics workflow for single-cell samples on the Orbitrap Astral mass spectrometer Authors Goal Tabiwang N. Arrey,1 Eugen Damoc,1 Assess proteome coverage and sample throughput performance for single-cell samples Bernard Delanghe,1 Fernanda Salvato,2…

Application note | 003350 Omics Orbitrap Astral mass spectrometer allows comprehensive proteome coverage at the single-cell level Authors Highlights Haoran Huang , Zilu Ye , Min Huang , 1 2 1 • The automatic single cell sorting pretreatment method is…

Technical note | 002780 Omics Deeper proteome coverage and faster throughput for single-cell samples on the Orbitrap Astral mass spectrometer Goal Authors To assess proteome coverage and sample throughput performance for single-cell Tabiwang N. Arrey1, Santosh Renuse2, Jenny Ho ,…