Aggregate Analysis of Adeno-Associated Viruses and Virus-Like Particles in Biopharma by Liquid Chromatography

SEC for Ultra-Large Analytes Column Selection and Method Development for Next Generation Biotherapeutics Anne Blackwell, PhD Bio LC Columns Product Manager Agilent Technologies 1 DE-005324 Size Exclusion Chromatography (SEC) Separation by size in solution Sample Types & Their Sizes Peptides…

Aggregate Analysis of Biotherapeutics Agilent size exclusion columns Accurately determine biomolecule aggregation and fragmentation Size exclusion chromatography (SEC) is a technique for separating proteins, oligonucleotides, and other complex biopolymers by size, using aqueous eluents. It is an essential tool for…

Consumables Workflow Ordering Guide Adeno-Associated Virus Identity Confirmation in Biopharma by LC/MS While adeno-associated viruses (AAVs) have their own unique set of critical quality attributes, many of the traditional assays used to monitor more established proteinbased therapeutics can still be…

High-Speed, High-Resolution Aggregate Analysis of Ultralarge Biotherapeutics Agilent AdvanceBio SEC 2.7 µm columns with 500 and 1000 Å pores Optimal pore sizes for your ultralarge biotherapeutics analyses Adeno-associated viruses (AAV), virus-like particles (VLP), oligonucleotides, and lipid nanoparticles (LNP) represent the…