Modernizing USP Melatonin Monograph Assay and Impurities Methods for Increased Throughput and Reduced Solvent Waste

Application Note Modernizing USP Melatonin Monograph Assay and Impurities Methods (II) – Analytical performance and Analysis of Dietary Supplements Jinchuan Yang, Paul D. Rainville Waters Corporation Abstract The USP Melatonin procedures for assay and impurities were previously optimized on an…

Application Note Reductions in Cost and Time by Modernizing a USP Monograph Method from HPLC to UHPLC and UPLC Instrumentation and Columns Kenneth D. Berthelette, Jennifer M. Nguyen, Jonathan E. Turner, Denis Savage Waters Corporation Abstract Modernization of the USP…

MODERNIZATION OF AN ANTIVIRAL IMPURITIES MONOGRAPH USING THE GLOBALLY HARMONIZED PHARMACOPEIAL GUIDANCE FOR LIQUID CHROMATOGRAPHY Catharine E. Layton, Paul D. Rainville, Michael Baynham Waters Corporation, 34 Maple St., Milford, MA, USA INTRODUCTION The U.S. Pharmacopeia USP portfolio of solutions addresses…

Application Note Improving USP Monograph Analysis Time Through Scaling by N on an HPLC System Using CORTECS™ Premier Columns Kenneth D. Berthelette, Maureen DeLoffi, Melissa Aiello, Kim Haynes Waters Corporation Abstract The United States Pharmacopeia General Chapter <621> allows certain…