NBC: Modification of Particle and Hardware Surfaces for Efficient Biotherapeutic Method Development

Application Note Accelerating Charge Variant Analysis of Biotherapeutics with the BioAccord™ System Robert E. Birdsall, Brooke M. Koshel, Ying Qing Yu Waters Corporation Abstract Ion Exchange Chromatography (IEX) is a valuable technique given its ability to resolve product/process related charge…

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[ APPLICATION NOTE ] Online IEX-MS of mAb Charge Variants Using a BioResolve SCX mAb Column, IonHance CX-MS pH Concentrates, and BioAccord System Samantha Ippoliti, Andrew Schmudlach, Matthew A. Lauber, and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION…

[ APPLICATION NOTE ] Optimizing LC-MS Separations of mAbs using a BioResolve SCX mAb Column and IonHance CX-MS pH Concentrates Andrew Schmudlach, Samantha Ippoliti, Qi Wang, and Matthew A. Lauber Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION A novel…