Analysis of Aminoglycoside Antibiotics by Reversed-Phase HPLC

Application Note 267 Analysis of the Aminoglycoside Antibiotics Kanamycin and Amikacin Matches USP Requirements INTRODUCTION Kanamycin and amikacin are broad-spectrum aminoglycoside antibiotics that are closely related (Figure 1). Kanamycin, used to treat a wide variety of serious gram-negative-bacterial infections, is…

Application Note 267 Analysis of the Aminoglycoside Antibiotics Kanamycin and Amikacin Matches USP Requirements INTRODUCTION Kanamycin and amikacin are broad-spectrum aminoglycoside antibiotics that are closely related (Figure 1). Kanamycin, used to treat a wide variety of serious gram-negative-bacterial infections, is…

Apramycin is an antibiotic used in veterinary medicine. Reported methods for apramycin and impurities analysis usually involves pre- or post column derivatization followed by UV detection2,3. Such approaches are tedious and time consuming, and may not be able to detect…

Poster Reprint ASMS 2026 TP 134 Quantitation of Aminoglycosides group of veterinary drugs in milk samples using LCMS/MS without ion pairing agents in the mobile phase Saikat Banerjee1, Prasanth Joseph1, Vinayak Azhakaprakalam,1 Vivek Dhyani1, Aimei Zou2 1Agilent Technologies, Bangalore, India…