Efficient Method Development of Small Interfering RNA by Reversed-Phase Ion-Pair Chromatograph

Application News LabSolutions™ MD : Software for Efficient Method Development based on Analytical Quality by Design Efficient Method Development of Oligonucleotides by Reversed-Phase Ion-Pair Chromatography Shinichi Fujisaki and Risa Suzuki User Benefits  LabSolutions MD can improve the efficiency of…

Customer application note | 004514 Pharma Efficient early-phase screening of siRNA purity and impurities via denaturing IP-RPLC-UV with a dual-channel UHPLC system Authors Application benefits Martina Lioi, Selin Bagci, David Benda, • Increased efficiency and time savings: Parallel scouting across…

Liquid Chromatograph Mass Spectrometer LCMS-9050 Application News Reversed-Phase Ion-Pair LC/MS Analysis of siRNA under Denaturing and Non-Denaturing Conditions Junna Nakazono User Benefits  The LCMS-9050 quadrupole time-of-flight mass spectrometer can be used to characterize siRNA.  The elution of siRNA…

MP 534 Practical LC–MS Workflows for siRNA and sgRNA Characterization Using a Single-Quadrupole Mass Spectrometer Vikki Johnson1, Kathleen Luo1, Risa Suzuki1,2, Atsuhiko Toyama1,2, Jeff Dahl1, Kosuke Uchiyama2, Toshiya Matsubara1 (1) Shimadzu Scientific Instruments, Columbia, MD. (2) Shimadzu Corporation, Kyoto, Japan.…