Improved Hydrophilic Interaction Liquid Chromatography for LC/MS Analysis of Released N-Glycans

Application Note Biopharma/Pharma Improved Hydrophilic Interaction Liquid Chromatography for LC/FLD/MS Analysis of Released N-Glycans Authors Abstract Randall Robinson, Tom Rice, Anne Blackwell, Aled Jones, and Oscar Potter Agilent Technologies, Inc. Glycosylation directly impacts protein functionality and is frequently monitored as…

Application Note Pharma and Biopharma Glycan Peak Assignment Tool (GPAT) Novel glucose unit-based software enabling more accurate peak assignments for InstantPC and 2-AB N-glycan HILIC/FLD analysis using the AdvanceBio Amide HILIC column and mobile phase Authors Abstract Randall Robinson, Tom…

Application Note Biopharma/Pharma Sensitive and Repeatable Analysis of InstantPC-labeled N-Glycans from Human Immunoglobulin G Enabling confident detection and quantification of low-abundance IgG glycans with UHPLC peak fidelity and excellent run-to-run precision Author Adem Cakar Agilent Technologies, Inc. Abstract Glycosylation is…

Application Note Pharma & Biopharma A Workflow for Rapid Sample Preparation and Exoglycosidase Characterization of N-Glycans in Antibodies Authors Yongjing Xie, Letícia Martins Mota, and Michael Butler National Institute for Bioprocessing Research and Training (NIBRT), Foster Avenue, Mount Merrion, Blackrock,…