Increasing the depth of single shot proteomics with enhanced data acquisition and processing strategies

Optimization of wide window acquisition methods for improved proteome coverage Tabiwang N. Arrey1, Bernard Delanghe1, David Horn2, Daniel Hermanson2, Daniel Zolg3, and Martin Frejno3 1Thermo Fisher Scientific GmbH, Bremen, Germany; 2Thermo Fisher Scientific, San Jose, CA, USA; 3MSAID GmbH, Garching…

Increased Dynamic Range of DDA-based label-free quantification using the CHIMERYS algorithm David M. Horn,1 Kai Fritzemeier,2 Katja Tham,2 Frank Berg,2 Daniel Hermanson,1 Tobias Schmidt,3 Daniel Zolg,3 Martin Frejno,3 and Bernard Delanghe2, 1Thermo Fisher Scientific, 355 River Oaks Parkway, San Jose,…

The intelligent protein informatics platform Thermo Scientific Proteome Discoverer software Transform proteomics mass spectrometry data into insights Thermo Scientific™ Proteome Discoverer™ software enables comprehensive proteomics data processing workflows empowered by artificial intelligence. • Powerful and flexible framework: Optimized analysis for…

Mass spectrometry Proteome Discoverer 3.0 software with the CHIMERYS intelligent search algorithm comparison to previous strategies, CHIMERYS finds more PSMs Current generation proteomics data analysis tools are unable to per tandem mass spectrum and markedly improves the spectrometers. Tandem mass…