Automated High-Throughput Analytical- Scale Monoclonal Antibody Purification Using Production-Scale Protein A Affinity Chromatography Resin

[APPLICATION NOTEBOOK] At-line Solutions for Upstream Bioprocessing Application Notes [APPLICATION NOTEBOOK] Introduction Bioprocessing harnesses the power of living cells to manufacture valuable products such as biological drugs for clinical use. The introduction and use of biologics has revolutionized biotherapeutics to…

Application Note Analytical Scale 96-well Protein A Affinity Resin-Based Purification using Andrew+™ Automation Robot Supporting Upstream Bioprocessing Yun W Alelyunasa, Julie Wushenskya, Mark Wronab, Rui Chena a Waters IMMERSE™ Lab, Newark, DE, United States b Waters Corporation, Milford, MA, United…

Application Note Analytical LC-MS Platform Methodologies to Support Upstream Bioprocess Optimization Yun Alelyunas, Julie Wushensky, Jurgen Sanes, Mark Wrona, Rui Chen Waters Corporation, United States Published on August 18, 2025 Introduction Effective process monitoring and product critical quality attribute analysis…

Application Note Automated High-Throughput N-Glycan Labelling and LC-MS Analysis for Protein A Purified Monoclonal Antibodies Caitlin M. Hanna, Stephan M. Koza, Ying Qing Yu Waters Corporation Abstract N-Glycans are routinely monitored during the development of biotherapeutics because they can affect…