Ultra-High-Resolution Separation of Oligonucleotides on Pellicular Anion-Exchange UHPLC Columns

0 Introduction 100 80 Relative Abundance Synthetic ONs with different functionalities including antisense ONs, small interfering RNAs (siRNAs), aptamers and immunostimulatory RNAs (isRNAs) are candidate therapeutic agents due to their specificity, and well-established synthesis and modification technologies. Still characterization is…

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