Determination of Streptomycin and Impurities Using HPAE-PAD

Application Note 66 Determination of Neomycin B and Impurities Using HPAE-IPAD INTRODUCTION Neomycin is a complex of water-soluble aminoglycoside antibiotics purified from the fermentation of the actinomycete Streptomyces fradiae and used in a variety of pharmaceutical applications, including topical, ophthalmic,…

Application Note 267 Analysis of the Aminoglycoside Antibiotics Kanamycin and Amikacin Matches USP Requirements INTRODUCTION Kanamycin and amikacin are broad-spectrum aminoglycoside antibiotics that are closely related (Figure 1). Kanamycin, used to treat a wide variety of serious gram-negative-bacterial infections, is…

Application Note 267 Analysis of the Aminoglycoside Antibiotics Kanamycin and Amikacin Matches USP Requirements INTRODUCTION Kanamycin and amikacin are broad-spectrum aminoglycoside antibiotics that are closely related (Figure 1). Kanamycin, used to treat a wide variety of serious gram-negative-bacterial infections, is…

APPLICATION NOTE 72647 Determination of gentamicin and related impurities in gentamicin sulfate Authors Jingli Hu and Jeffrey Rohrer Thermo Fisher Scientific Sunnyvale, CA Goal To validate the gentamicin sulfate United States Pharmacopeia (USP) monograph method for gentamicin composition and impurities…