Ternary Gradient for Tenofovir Disoproxil Fumarate Impurity Profiling

Susanne Fabel and Markus Martin Thermo Fisher Scientific, Germering, Germany Appli cat i on N ote 1 1 2 9 Ternary Gradient for Tenofovir Disoproxil Fumarate Impurity Profiling Key Words USP, Aqueous Gradient, Active Pharmaceutical Ingredient, Equilibration, Accucore aQ Column…

APPLICATION NOTE 72391 Achieve confident impurity detection with the Thermo Scientific ISQ EC single quadrupole mass spectrometer Authors Goal Stephan Meding, Katherine Lovejoy, Martin Ruehl Thermo Fisher Scientific, Germering, Germany Demonstrate quantitative impurity analysis with the Thermo Scientific™ ISQ™ EC™…

APPLICATION NOTE 72944 Quantitation of tenofovir and impurities in multi-component drug products by ternary gradient reversed-phase chromatography with charged aerosol detection Author Katherine Lovejoy Thermo Fisher Scientific, Germering, Germany Application benefits • Improves single-calibrant quantitation of charged analytes by taking…

APPLICATION NOTE 72944 Quantitation of tenofovir and impurities in multi-component drug products by ternary gradient reversed-phase chromatography with charged aerosol detection Author Katherine Lovejoy Thermo Fisher Scientific, Germering, Germany Application benefits • Improves single-calibrant quantitation of charged analytes by taking…