Quantitative Analysis of Warfarin Tablets Containing Salt-Form Impurities Using Transmission Raman Spectroscopy

Guide to TRS100 Analytical Method Development Table of contents Foreword3 1. Introduction 5 1.1 Method development considerations 1.2 Measurement of success 1.3 Overview of life cycle 6 8 8 2. Fundamentals 9 2.1 Raman spectroscopy 2.2 Chemometrics 2.3 Units 9…

Application Note Pharmaceuticals Supporting Continuous Manufacturing of Drug Products with Transmission Raman Spectroscopy Fast at-line analysis using an Agilent TRS100 adds analytical insight to existing in-line PAT Author Julia Griffen Agilent Technologies, Inc. Abstract Continuous manufacturing (CM) of oral solid…

Application Note Polymorph Analysis Quantification of Crystallinity Using Transmission Raman Spectroscopy CRYSTALLINE AMORPHOUS Authors Julia Griffen and Andrew Owen Agilent Technologies, Inc. Abstract The crystallinity of an active pharmaceutical ingredient (API) may affect its bio‑availability and its overall patient efficacy.…

Application Note Pharmaceuticals Evaluating Repeatability and Sensitivity of Transmission Raman Spectroscopy Comparing measurements of API standards by Agilent TRS100 quantitative pharmaceutical analysis system with HPLC Author Marco Pinto, PhD Agilent Technologies, Inc. Abstract Transmission Raman Spectroscopy (TRS) is a scattering…