Quantitation of Oxidation Sites on a Monoclonal Antibody Using an Agilent 1260 Infinity HPLC-Chip/MS System Coupled to an Accurate-Mass 6520 Q-TOF LC/MS

Identification of Oxidation Sites on a Monoclonal Antibody Using an Agilent 1260 Infinity HPLC-Chip/MS System Coupled to an Accurate-Mass 6520 Q-TOF LC/MS Application Note Authors Abstract Ravindra Gudihal Agilent Technologies India Pvt. Ltd. Bangalore, India The identification of oxidation sites…

Application Note Biopharma/Pharma Peptide Mapping and Quantitation of Oxidation and Deamidation in Monoclonal Antibodies Author Yulan Bian Agilent Technologies, Inc. Abstract This application note demonstrates an integrated workflow of peptide mapping and quantitation of chemical-induced oxidation and deamidation in monoclonal…

Peptide Mapping of Innovator and Biosimilar Monoclonal Antibody Using an Agilent 1290 Infinity UHPLC Coupled to an Agilent 6550 iFunnel Q-TOF LC/MS System Application Note Author Introduction Ravindra Gudihal Monoclonal antibodies (mAbs) are becoming one of the important classes of…

Application Note Biotherapeutics Quantitation of Chemical-Induced Deamidation and Oxidation on Monoclonal Antibodies Using Agilent 6545XT AdvanceBio LC/Q-TOF and Agilent MassHunter BioConfirm Software Author Linfeng Wu Agilent Technologies, Inc. Santa Clara, CA, USA Introduction Modifications such as asparagine (Asn) deamidation, aspartate…