Multi-Attribute Methods for Biopharmaceutical Analysis

[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…

CASE STUDY 73683 Deploying the multi-attribute method (MAM) across sites at Pfizer Pfizer is building the MAM lab-of-the-future Pfizer is a leading research-based biopharmaceutical company. At Pfizer, scientific principles, innovation, and the company’s global resources are applied to bring therapies…

Application Note The BioAccord System With ACQUITY Premier for Improved Peptide CQA Monitoring Nilini Ranbaduge, Robert E. Birdsall, Ying Qing Yu, Weibin Chen Waters Corporation Abstract Peptide MAM is an LC-MS based assay for direct biotherapeutic product attribute analysis that…

Application Note Extending the Capabilities of the BioAccord LC-MS System with a streamlined workflow for compliant-ready Multi-Attribute Method (MAM) Nilini Ranbaduge, Ying Qing Yu Waters Corporation This is an Application Brief and does not contain a detailed Experimental section. Abstract…