855 Robotic Titrosampler

Significance of the topic

The integration of automatic sample preparation and titrimetric analysis addresses critical needs in modern analytical laboratories. By combining robotics and high-performance titration, laboratories can achieve greater throughput, enhanced reproducibility, and significant bench-space savings. This development supports quality control, environmental monitoring, pharmaceutical testing, and routine industrial analysis by reducing manual intervention and associated variability.

Goals and overview of the system

This document presents the 855 Robotic Titrosampler, an all-in-one solution that unites a high-performance titrator and a robotic sample processor in a compact footprint. The primary objectives are to streamline workflows, minimize bench space by up to 40%, and accelerate the analysis of large sample series with reliable precision.

Methodology and instrumentation

The core components of the system include:

• 855 Robotic Titrosampler: Integrates a built-in titrator and sample handling unit.
• 900 Touch Control: A benchtop interface for standalone operation without a PC.
• OMNIS Software: A PC-based titration platform offering flexible method setup, parallel step execution, and database storage.
• Accessories: Modular sample racks, swing head, robotic arm, peristaltic or membrane pumps, sensors, electrodes, and stirrers.

Users can select the Light version for medium throughput (10–50 samples) or upgrade to the Basic version for higher capacity. Retrofit options allow adding sample racks or burets to scale operations without replacing the entire system.

Main results and discussion

Key performance outcomes demonstrated:

• Bench-space reduction by 40% compared to discrete titrator and autosampler setups.
• High reproducibility and accuracy across multiple sample types.
• Throughput enhancement via automatic cleaning, conditioning, and flexible rack configurations.
• Reliable unattended operation, enabling overnight and weekend runs.
• Simple scalability: Light version conversion to Basic version and addition of pump units.

The touchscreen interface and OMNIS software ensure full process transparency and easy monitoring of method execution.

Benefits and practical applications

Implementing the 855 Robotic Titrosampler yields:

• Time savings by automating routine titration tasks.
• Improved data consistency for QA/QC labs.
• Space optimization in crowded analytical benches.
• Adaptability to acid/base, TAN/TBN, chloride, and fluoride determinations.
• Cost efficiency through modular upgrades rather than full system replacements.

Typical application fields include environmental water analysis, food and beverage quality testing, petrochemical titrations, and pharmaceutical assays.

Future trends and opportunities

Advancements may include integration with advanced sample pretreatment modules (e.g., extraction, dilution), expanded sensor libraries for new analytes, and enhanced connectivity for laboratory information management systems (LIMS). The trend toward miniaturization and mobile automation could lead to portable robotic titration units for on-site analysis.

Conclusion

The 855 Robotic Titrosampler represents a significant step forward in automating titrimetric workflows. Its compact design, modularity, and robust software control offer laboratories a versatile platform to boost productivity, accuracy, and operational efficiency.

Reference

• Metrohm AG. 855 Robotic Titrosampler integrated system brochure (8.855.5002EN), February 2022.