A Systematic Quick Method Development Approach to Optimize Protein Size Exclusion Chromatography

Application Note Optimized Method Conditions for mRNA Characterization by SEC-MALS With GTxResolve™ Premier SEC 1000 Å 3 µm Columns Lavelay Kizekai, Bretton Fletcher, Szabolcs Fekete, Balasubrahmanyam Addepalli, Sophia Kendrick, Michelle Chen, Matthew A. Lauber Waters Corporation, Wyatt Technology Abstract Detailed…

[ APPLICATION NOTEBOOK ] SIZE-EXCLUSION CHROMATOGRAPHY (SEC) OF PEPTIDES, PROTEINS, AND AAVs [ SIZE-EXCLUSION CHROMATOGRAPHY ] [ SIZE-EXCLUSION CHROMATOGRAPHY ] Introduction Gel-permeation chromatography (GPC), size-exclusion chromatography (SEC), and gel-filtration chromatography (GFC) are commonly used terms to describe a liquid chromatographic…

Agilent Biocolumns Aggregate/Fragment Analysis Application Compendium Contents Background 2 Getting Started 3 How to Guide - Size Exclusion Chromatography for Biomolecule Analysis - 5991-3651EN 4 Featured Application Notes Elevate Your mAb Aggregate Analysis - 5994-2709EN 1 22 22 High-Resolution, High-Throughput…

[ APPLICATION NOTE ] Size-Exclusion Chromatography Analysis of Adeno-Associated Virus (AAV) Preparations Using a 450 Å Diol-Bonded BEH Column and Fluorescence Detection Stephan M. Koza and Weibin Chen Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ ■ Optimization of SEC…