Ensuring precise isolation of macromolecules by hyphenating UHPLC separation power with exact fractionation for analytical and semi-preparative LC purification

Technical note | 72940 HPLC & UHPLC Principles of fraction collection using the Vanquish HPLC and UHPLC systems Authors Dennis Köhler1, Susanne Fabel1, Ian Acworth2, Guobin Shen3 Thermo Fisher Scientific, Germering, Germany; Thermo Fisher 1 2 Scientific, Chelmsford, MA, USA;…

Customer application note | 001641 Pharma Semi-preparative reversed-phase liquid chromatographic purification of oligonucleotides Authors Application benefits Dennis Köhler , Dr. Anna Spanopoulou , 1 2 • Incorporation of the Thermo Scientific™ Vanquish™ LC platform into the production workflow of an…

TECHNICAL NOTE 72940 Principles of fraction collection using the Vanquish UHPLC systems Authors Introduction Dennis Koehler, Thermo Fisher Scientific, Germering, Germany The principle of liquid fraction collection is an evolving science whose tools have developed into automated sample introduction, precise…

Technical note | 002751 HPLC and UHPLC Setting the start position for flexible fraction collection by using custom variables in Chromeleon CDS Goals Authors Lei Shi , Yongqiang Li , Ying Liu , Li Gao , To show that the…