Streamlined LC-MS Analysis of Stress Induced Impurities of a Synthetic Peptide using the BioAccord System and the waters_connect Intact Mass Application

Application Note Accelerating GLP-1 Development with HighThroughput LC-MS Using the BioAccord™ LC MS System and the INTACT Mass Application Jonathan Fox, Laetitia Denbigh, Scott Berger, Nick Pittman Waters Corporation, United States Published on December 17, 2025 Abstract High-quality analysis of…

[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…

Application Note LC-MS Analysis of siRNA, Single Guide RNA and Impurities Using the BioAccord™ System with ACQUITY™ Premier and New Automated INTACT Mass Application Catalin E. Doneanu, Patrick Boyce, Henry Shion, Joseph Fredette, Scott J. Berger, Heidi Gastall, Ying Qing…

Application Note Higher Throughput Intact Mass Confirmation and Impurity Screening of GLP-1 Analogues Using Multi-Reflecting TOF Technology and INTACT Mass 1.9 Application Jonathan Fox, Scott J Berger, Laetitia Denbigh, Ying Qing Yu Waters Corporation, United States Published on July 14,…