EAS: Considerations for HILIC Method Migration

NEEDLE WASH MECHANISM AND ITS IMPACT ON HILIC ANALYSIS E. Pedanou, K. Witter, N. Wong, J. Simeone, and P. Hong Waters Corporation, Milford, MA, USA INTRODUCTION 0.015 AU 0.010 0.005 Alliance iS HPLC System 1 2 80:20 Acetonitrile:Water 1 2…

[ APPLICATION NOTE ] Modernization and Troubleshooting of the USP Organic Impurity Method for Cetirizine Hydrochloride Tablets: Demonstration of XBridge HILIC Robustness Capabilities Across HPLC and UHPLC Instruments Jyotsna Sehajpal and Jacob Fairchild Waters Corporation, Milford, MA, USA APPLICATION BENEFITS…

Alliance iS HPLC System: A New Era of Intuitive Simplicity HPLC Analysis Water-Soluble Vitamins Hydrophilic Interaction Troubleshooting Peak Splitting Azithromycin Analysis Atorvastatin Analysis Pharmaceutical Drug Analysis Method Migration Naphazoline Hydrochloride and Pheniramine Maleate Method Modernization Chlorhexidine Carryover USP Ibuprofen Assay…

W0930-06-32 Applying Quality by Design Principles to the Migration of a Compendial Method between Multiple HPLC Systems Lise Gauthier, Paula Hong Waters Corporation, Milford, MA 01757 CONTACT INFORMATION: [email protected]. PURPOSE RESULT(S) Within the pharmaceutical industry, compendial LC methods are used…