Optimized ELSD Workflow for Improved Detection of Lipid Nanoparticle Components

LabSolutions MD : Software for Efficient Method Development based on Analytical Quality by Design Application News Efficient Method Development of Lipid Nanoparticle Components Using ELSD Shinichi Fujisaki User Benefits  LabSolutions MD enables efficient optimization of separation conditions for lipid…

Application Note Rapid Analysis of Lipid Nanoparticle Components Using BioAccord LC-MS System Giorgis Isaac, Nilini Ranbaduge, Bonnie A. Alden, Colette Quinn, Weibin Chen, Robert S. Plumb Waters Corporation Abstract The recent success of mRNA vaccines for COVID-19 is in part…

Lipid Nanoparticle Impurity Monitoring Using Single Quadrupole Mass Detection for Regulated Environments Authors: Duanduan Han, Kellen DeLaney, Robert E. Birdsall, Ying Qing Yu Affiliation: Waters Corporation, Milford, MA Results Introduction Lipid Nanoparticles UV 3 AU 2 Cholesterol • Important for…

Application Note Lipid Nanoparticle Analysis: Leveraging MS to Reduce Risk Duanduan Han, Kellen DeLaney, Bonnie A. Alden, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract Lipid nanoparticles (LNPs) represent an elegant solution in the delivery of gene-based therapeutics that…