Conformational Studies Using Second Derivative UV-Vis Absorption Spectroscopy

Application Note Biopharmaceuticals Determination of Protein Extinction Coefficients and Concentration by UV‑Vis Enhancing lab efficiency and productivity with the Agilent Cary 3500 Multicell UV-Vis Spectrophotometer Author Aveline Neo Agilent Technologies, Inc. Abstract This study highlights the advanced capabilities of the…

Application Note Biopharmaceuticals Aggregation Analysis of Innovator and Biosimilar Therapeutic Proteins Using FTIR Measurement of rituximab aggregation in concentrated samples using the Agilent Cary 630 FTIR spectrometer Authors Aveline Neo and Ravindra Gudihal Agilent Technologies, Inc. Abstract Protein aggregation can…

Application Note Biopharma/Pharma Hybrid UV-Vis/MS Assay for Free Cysteine Determination in Monoclonal Antibodies Using the Agilent Cary 3500 UV-Vis and Agilent 6545XT AdvanceBio LC/Q-TOF MS Author Abstract Ravindra Gudihal Agilent Technologies, Inc. Cysteine residues in monoclonal antibodies (mAbs) play key…

Technical Overview Characterization of Biomolecules using High-Performance UV-Vis Spectrophotometry Accelerating research into oligonucleotides and proteins with the Agilent Cary 3500 UV-Vis Author Introduction Wesam Alwan Agilent Technologies, Inc. Molecular biology research plays a vital role in understanding biochemical and molecular…