SYNAPT HDMS: Improving Ion Mobility Separation by Increasing Drift-Gas Polarizability

[ APPLICATION NOTEBOOK ] STRUCTURAL ELUCIDATION 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Traditional Herbal Medicine Structural Elucidation using SYNAPT HDMS with Time-Aligned Parallel…

Gas-Phase Separation of Benzocaine Protonation Site Isomers and Phenylalanine Using Travelling-Wave Ion Mobility MS Jonathan P. Williams,1 Martin Palmer,1 Jasper Boschmans,2 Filip Lemière,2 and Frank Sobott2,3 1 Waters Corporation, Wilmslow, UK; 2 Biomolecular and Analytical Mass Spectrometry Group, Department of…

Determination and Characterization of Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS’s) in Environmental Samples Using UPLC Ion Mobility MS Michael McCullagh, 1Mike Hodgkinson, 1 Leonard Dillon, 2 Bert van Bavel, 3 Jennifer A. Burgess, and 2 Ingrid Ericson Jogsten Waters Corporation, Wilmslow,…

Identification of Multiple Sites of Intra-Molecular Protonation and Different Fragmentation Patterns within the Fluoroquinolone Class of Antibiotics in Porcine Muscle Extracts Using Travelling Wave Ion Mobility Mass Spectrometry Mike McCullagh,1 Sara Stead,1 Jonathan Williams,1 Wouter de Keizer,2 and Aldert Bergwerff…