Dimethylamine in Metformin

Suparerk Tukkeeree,1 Thunyarat Phesatcha,1 Jeffrey Rohrer2 1 Thermo Fisher Scientific Inc., Bangkok, Thailand; 2Thermo Fisher Scientific Inc., Sunnyvale, CA USA Key Words Equipment Type 2 Diabetes, Reagent-Free Ion Chromatography (RFIC), Dionex IonPac CS19 Column, Pharmaceuticals • Thermo Scientific Dionex ICS-2000…

Nitrosamine impurities in drug substances / LCMSTM-9030 Application News Detection and Quantitation of Nitrosamine Impurities in Drug Substances by LC-HRMS on LCMS-9030 Zhaoqi Zhan1, Zhe Sun1, Deepti Bhandarkar2, Shailendra Rane2, Pratap Rasam2, Jitendra Kelkar2 (Asia Pacific) Pte Ltd, 2 Shimadzu…

APPLICATION NOTE 000235 Simultaneous quantitation of nine nitrosamines using a highly sensitive and LC-HRAM mass spectrometry method in multiple drug products Authors: Krishna Mane, Pratip Saha, Venkatesh Chanukuppa, Biswajayee Patra, Saravanan Kumar Thermo Fisher Scientific, Bengaluru, India Keywords: Nitrosamine quantitation,…

Thunyarat Phesatcha,1 Suparerk Tukkeeree,1 and Jeff Rohrer2 Thermo Fisher Scientific, Bangkok, Thailand; 2Thermo Fisher Scientific, Sunnyvale, CA, USA 1 Key Words Pharmaceutical, Dionex IonPac CS19 Column, Reagent-Free Ion Chromatography Introduction Methylamine or monomethylamine (MMA) is widely used in different stages…