Combination of Bottom-Up and Top-Down Characterization of Biologics Using a High Throughput Capable Workflow in Proteome Discoverer Software

Middle-down Analysis of Monoclonal Antibody Middle using Nano-flow Liquid Chromatography and a Novel Tribrid Orbitrap Mass Spectrometer Jie Qian,1 Keith A. Waddell, 2 Zhiqi Hao2 1 Thermo Fisher Scientific, Somerset, NJ, 2Thermo Fisher Scientific San Jose, CA Overview Results Purpose:…

Proteome Discoverer software is a node-based workflow engine and study management platform for analysis of mass spectrometry-based proteomics datasets. The latest released version 2.1 fully supports isotopically-labeled quantitative workflows, such as TMTTM reporter ion-based quantification and SILAC precursor ion quantification,…

1000 Proteins Per Hour [pph] – Maximizing Protein ID From Complex Mixtures Kai Scheffler1, Eugen Damoc2, and Thomas Moehring2 Thermo Fisher Scientific, Scientific 1 Dreieich, Dreieich Germany; 2 Bremen, Bremen Germany Results: R lt The Th iincreased d sensitivity iti…

The intelligent protein informatics platform Thermo Scientific Proteome Discoverer software Transform proteomics mass spectrometry data into insights Thermo Scientific™ Proteome Discoverer™ software enables comprehensive proteomics data processing workflows empowered by artificial intelligence. • Powerful and flexible framework: Optimized analysis for…