Retention Time Based FAIMS Depletion of Protein Drugs in Peptide Mapping to Increase Coverage of Background Host Cell Proteins

APPLICATION NOTE 65902 Improving targeted peptide quantification Combining a TSQ Altis with a FAIMS Pro interface for peptides in complex matrices Authors: Michael Volný, Cornelia L. Boeser, Michael W. Belford, Claudia P. B. Martins, Mary L. Blackburn Thermo Fisher Scientific,…

Reliable and Deep Proteome Coverage by Gas-Phase Fractionation of Peptides with a FAIMS Pro Interface on a Modified Quadrupole Orbitrap Julia Kraegenbring1, Tabiwang N. Arrey1, Michael W. Belford2, Satendra Prasad2, Kerstin Strupat1, Markus Kellmann1, Thomas Moehring1, and Alexander Harder1 1Thermo…

Comprehensive Evaluation of Bottom-up Proteomics using an Orbitrap Fusion Lumos Tribrid Mass Spectrometer with FAIMS Pro Interface Yue Zhou, Mo Hu, Min Huang, Xiangyun Yang, Jing Li, Thermo Fisher Scientific, Building 6, 27 Xinjinqiao Road, Shanghai, China, 210006 ABSTRACT RESULTS…

Accelerate your Proteomic Workflow with the Thermo Scientific™ FAIMS Pro™ Interface Proteomics is the systematic and simultaneous study of numerous and diverse proteins. Its emergence was catalyzed by the realization that complexity is principally generated by protein variation, rather than…