DEPLOYING EFFICIENT WORKFLOWS FOR PEPTIDE MAPPING WITH LC-UV/MS PLATFORMS

Application Note Improving Peptide Mapping Studies and Reducing Assay Failures Through Reproducible Performance Using the ACQUITY Premier UPLC System (BSM) Kellen DeLaney, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract Reproducibility of liquid chromatography (LC) systems is critical in…

Application Note Utilizing Empower™ Software to Streamline and Automate the Detection of Sample-toSample Differences within Peptide Maps of Biopharmaceuticals Kellen DeLaney, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract High-throughput biopharmaceutical workflows require efficient data analysis to minimize analysis…

Application Note Method Scaling from ACQUITY™ Premier to Arc™ Premier System Xiangsha Du, Kellen DeLaney, Robert E. Birdsall, Tatyana Friedman Waters Corporation Abstract Instruments capable of delivering consistent and reproducible results are highly desirable for efficient development and manufacturing of…

[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…