Bottom-up and Top-down Disulfide Bond Mapping of Beta-lactoglobulin on a Q-TOF with the Capability to Perform both CID and ECD

Poster Reprint ASMS 2023 Poster number TP 024 Top-down characterization of native monoclonal antibodies obtained with electron capture dissociation on Q-TOF instruments Yury V. Vasil’ev1, Rachel Franklin1, Michael C. Hare1, Adrian Guthals1, Joseph S. Beckman2 1e-MSion 97332 2Oregon – A…

Application Note Biopharma Top-Down Sequence Analysis of Intact Proteins Using an Agilent AdvanceBio 6545XT LC/Q-TOF with ExD Authors Rachel Franklin and Mike Hare Agilent Technologies, Inc. Abstract Detailed proteoform characterization is crucial for understanding disease mode of action (MOA) and…

Transformative Workflows for Protein Characterization: ECD and Multidimensional Separations Expert Insights Sponsored by Expert Insights Contents Introduction 3 The Role of Electron Capture Dissociation in Biomolecular Analysis Adapted from Cooper, et al. 4 Offline Coupling of Hydrophobic Interaction Chromatography– Capillary…

ExD AQ-25x Option AQ-251 • AQ-252 for Agilent LC/Q-TOF User Guide R011 • November 2023 Notices Notices About this Guide Patents The purpose of this document is to provide: This product is protected by U.S. patents 8,723,113 B2; 9,269,556 B2;…