Drug Metabolite Identification Using Waters™ SELECT SERIES™ Cyclic™ Ion Mobility Mass Spectrometer and waters_connect™ Application Manager

Application Note Rapid Identification of the In Vivo Biotransformations of a Targeted Protein Degrader (PROTACs) Using Xevo G3 QTof and waters_connect Software Platform Robert S. Plumb Waters Corporation, United States Published on June 05, 2025 Contact Sales Abstract PROteolysis TArgeting…

DOING MORE WITH LESS: ADDRESSING THE MICROSAMPLING SENSITIVITY CHALLENGE IN DMPK STUDIES USING VACUUM JACKETED COLUMN & UHPLC-CYCLIC ION MOBILITY MS Authors: Andrew Leightner1, Russell Mortishire-Smith2, Billy J. Molloy2, Robert S. Plumb1, Ian D. Wilson3, Affiliations: 1Waters Corporation, Milford, USA,…

[ APPLICATION NOTE ] Metabolite Identification of Complex Cyclic Peptides Using WebMetabase, Ion Mobility-Enabled DIA, and Product Ion Confirmation Mark Wrona Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ Ability to screen metabolism from The incorporation of unnatural amino acids,…

A P P LICAT ION SOLUT IONS FO R M ETABOLIT E IDENT IFICAT ION A P P L I C AT I O N S O L U T I O N S F O R M E TA…