Inline sample preparation – An effective tool for ion analysis in pharmaceutical products

Metrohm White paper IC: The all-rounder in pharmaceutical analysis Stephanie Kappes, Alfred Steinbach, and Katinka Ruth Ion chromatography is a flexible technique with a wide variety of practical uses in the pharma sector – here we take a look at…

Ion chromatography – the all-rounder for pharmaceutical analysis E. Suess1, C. Emmenegger1, S. Kappes1, M. Laeubli1, I. Reber1, K. Ruth1, A. Steinbach1, and G. Bogenschuetz2 Pharmaceutical solutions Active pharmaceutical ingredients (APIs) Pharmaceutical solutions denote isotonic, hemodialysis, or infusion solutions, containing…

Trace-level aliphatic amines in cationic pharmaceutical ingredients Summary Coupled-column matrix elimination (CCME) The analytical challenge treated by the present work consists in detecting sub-ppb concentrations of low-molecular-weight amines in the presence of strongly retained cationic drugs by using ion chromatography…

Application Note Pharmaceuticals Highly Sensitive LC/MS/MS Method for the Simultaneous Quantification of Mutagenic Azido Impurity Analogues in Five Different Sartan APIs and Formulations Detection of regulated genotoxic impurities from the drug manufacturing process Authors Kartheek Srinivas Chidella, Saikat Banerjee, and…