Enhanced Metabolite Identification Using Orbitrap Tribrid Mass Spectrometer

Enhanced Metabolite Identification using Orbitrap™ Tribrid Mass Spectrometer Shuguang Ma, Ph.D. Drug Metabolism and Pharmacokinetics Genentech, Inc. Thermo Fisher Scientific 2018 ASMS Breakfast Workshop, June 04, 2018 Outline  Introduction  Orbitrap ID-X with AcquireX Algorithm and Workflow  Case…

Optimized Workflow for Structure Elucidation of Pharmaceutically Relevant Extractables and Leachables Seema Sharma1, Kate Comstock1, Doug Kiehl2, Graeme McAlister1, Ryo Komatsuzaki1, Caroline Ding1, Ralf Tautenhahn1, Derek Bailey1, Linda Lin1, Tim Stratton1, Shannon Eliuk1, Iman Mohtashemi1, Jonathan Josephs1, Vlad Zabrouskov1 1Thermo…

Search for What’s Missing: Unknown Compound Characterization Using LC-MS Kate Comstock Sr. Marketing Specialist, Pharma/Biopharma Marketing The world leader in serving science Small Molecule Structure Analysis Small molecule structure analysis encompasses broad applications: Pharmaceutical, metabolomics, food & environmental, clinical, forensic,…

Improved Orbitrap Tribrid MS for Pharmaceutical Impurity Identification Fenghe Qiu1, Kate Comstock2, Seema Sharma2, Graeme McAlister2 1Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA 2Thermo Fisher Scientific, San Jose, CA, USA OVERVIEW DATA ACQUISITION USING AcquireX Purpose: Improving pharmaceutical impurity identification…