Site Requirements - Biotage Extrahera LV-200

Importance of the Topic

Automated solid-phase extraction workstations such as the Biotage Extrahera LV-200 are widely adopted in analytical and QA/QC laboratories to enhance throughput, reproducibility, and safety. Ensuring the correct site installations of these systems is critical to prevent sample contamination, equipment damage, and operator hazards. A well-prepared environment supports reliable operation and extends the lifetime of costly instrumentation.

Document Objectives and Overview

This document defines the essential site requirements for the successful delivery, installation, and demonstration of the Biotage Extrahera LV-200. It guides laboratory managers, facilities engineers, and end users through the necessary steps to prepare ventilation, space, utilities, and safety provisions. By following these recommendations, customers can avoid installation delays and incomplete system functions.

Methodology and Instrumentation

The requirements are organized by category: ventilation, mechanical support, environmental parameters, electrical, gas and vacuum supplies, and external fire protection. Each section details minimum specifications and, where applicable, tolerances for connectors and adapters. A checklist approach supports both customers and service engineers during installation and verification.

Used Instrumentation

• Biotage Extrahera LV-200 automated SPE workstation
• Air duct adapter (outer Ø 159.0 ± 0.3 mm; inner Ø 152.7 ± 0.3 mm)
• Gas tubing (6 mm Ø outer, 4 mm Ø inner)
• Pressure regulators and filters (ISO 8573-1 Class 1-x-1)
• Calibrated laboratory balance (0.0001 g accuracy)

Main Findings and Discussion

Ventilation

• The system must exhaust at least 6 m³/min via a dedicated fume hood or equivalent enclosure. For benchtop use without a hood, the supplied duct adapter and suitable tubing must connect to an external exhaust.

Mechanical Support and Dimensions

• Package weight: 125 kg; unpacked system weight: 80 kg.
• Package dimensions: 1230 × 840 × 800 mm. System footprint without touchscreen: 610 × 510 × 790 mm; with touchscreen: 860 × 570 × 790 mm.

Environmental Conditions

• Operating temperature: 18 °C–32 °C; relative humidity: 10 %–90 % RH.
• Ambient air must be free of visible particulates and smoke, comparable to normal laboratory standards.

Utilities

• Electrical: 100 V–240 V AC, 50/60 Hz, 300 VA, grounded outlet.
• Compressed air: 5 L/min at 6 ± 0.2 bar; nitrogen: 1 L/min during SPE and 70 L/min during plate drying at 6 ± 0.2 bar.
• Vacuum: partial pressure < 500 mbar, ≥ 8.3 L/min flow.

External Fire Protection

Local fire-safety measures should be installed for unattended operation to comply with regulations.

Benefits and Practical Applications

Adhering to these site requirements minimizes installation time, avoids operational interruptions, and protects analytical integrity. Proper gas filtration and exhaust management reduce contamination, while accurate environmental controls ensure reproducible extraction yields.

Future Trends and Opportunities

As laboratories move toward fully connected and automated workflows, future installations will incorporate remote monitoring of environmental parameters, predictive maintenance alerts, and integration with laboratory information management systems (LIMS). Advances in compact and high-efficiency filtration modules will further improve safety and reduce footprint requirements.

Conclusion

The Biotage Extrahera LV-200 site requirements document provides a comprehensive framework for laboratory preparation. Compliance with ventilation, utility, and environmental specifications is essential for safe, efficient, and reliable operation of automated SPE workflows.

References

No external references were cited.